Goette D K
J Am Acad Dermatol. 1980 Feb;2(2):148-54. doi: 10.1016/s0190-9622(80)80394-x.
Seventeen cases of clinically and histologically characteristic chondrodermatitis nodularis chronica helicis (CNCH) are presented. Thirteen histologic specimens revealed transepidermal elimination (TE) of necrobiotic material from the dermis. This elimination occurred through transepidermal channels, slits, or erosions overlying a dermal necrobiotic granuloma. The granuloma was surrounded by granulation tissue composed of histiocytes and lymphocytes. Telangiectasia and peripheral solar elastosis were common findings. The histologic features and clinical characteristics found predominantly in white men over 40 years of age suggest that CNCH etiologically and pathogenetically represents an actinically induced perforating necrobiotic granuloma.
本文报告了17例具有临床和组织学特征的慢性结节性耳轮皮炎(CNCH)。13份组织学标本显示坏死物质从真皮经表皮排出(TE)。这种排出是通过覆盖真皮坏死性肉芽肿的经表皮通道、裂隙或糜烂实现的。肉芽肿被由组织细胞和淋巴细胞组成的肉芽组织包围。毛细血管扩张和周边日光性弹性组织变性是常见表现。主要见于40岁以上白人男性的组织学特征和临床特点提示,CNCH在病因和发病机制上代表一种光化性诱导的穿通性坏死性肉芽肿。