Cadoret R J, Widmer R B, North C
J Fam Pract. 1980 Apr;10(4):625-9.
Somatic pain, functional, and anxiety complaints of 154 depressed patients were followed during the course of their initial depression and were found to parallel the depression: these complaints increased in number just prior to diagnosis of depression and decreased to normal levels after one year's treatment of the depression. Persistence of these types of somatic symptoms after one year's treatment predicted eventual chronicity of the depression. Older patients were also more likely to develop chronic depressions, and there was some indication that those individuals who had an initial remission of a depression followed by a second depression which then became chronic had longer first depressions.
对154名抑郁症患者的躯体疼痛、功能障碍及焦虑症状在其首次抑郁发作期间进行了跟踪观察,发现这些症状与抑郁情况平行:这些症状在抑郁症诊断前数量增加,在抑郁症治疗一年后降至正常水平。经过一年治疗后这些类型的躯体症状持续存在预示着抑郁症最终会发展为慢性。老年患者也更有可能发展为慢性抑郁症,并且有迹象表明,那些首次抑郁症缓解后又出现第二次抑郁症并最终发展为慢性的患者,其首次抑郁症发作的时间更长。