Wilkin J K, Rosenberg E W, Kanzaki T
Arch Dermatol. 1978 Dec;114(12):1795-6.
A 13-year-old white girl was admitted with pachyonychia congenita, Kumer and Loos type 1. In addition to all nails being distally elevated, plantar keratoses and bullae, and a scalloped tongue, the patient also had keratotic papules on the elbows and knees. A cornoid lamella was identified in the histologic examination of keratotic papule. The cornoid lamella, widely regarded as pathognomonic for porokeratosis (Mibeli) and its variants, may not be specific. This histologic marker should be sought in other localized disorders of keratinization.
一名13岁白人女孩因先天性厚甲症（库默尔和卢斯1型）入院。除所有指甲远端隆起、足底角化病和大疱以及扇贝状舌外，患者肘部和膝部还有角化性丘疹。在角化性丘疹的组织学检查中发现了角质层板。角质层板被广泛认为是汗孔角化症（米贝利型）及其变异型的特征性表现，但可能并不具有特异性。在其他局限性角化异常疾病中也应寻找这种组织学标志物。
