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来自非洲埃塞俄比亚动物地理区域的利什曼原虫的生化和血清学分类学

The biochemical and serological taxonomy of Leishmania from the Aethiopian zoogeographical region of Africa.

作者信息

Chance M L, Schnur L F, Thomas S C, Peters W

出版信息

Ann Trop Med Parasitol. 1978 Dec;72(6):533-42. doi: 10.1080/00034983.1978.11719357.

Abstract

The electrophoretic variation of the enzymes MDH, GPI, G6PGH, 6PGDH were determined for 68 strains of Leishmania isolated in the Aethiopian zoogeographical region. Other characters determined were the DNA buoyant density of nuclear and kinetoplast DNA and the excreted factor serotype. The strains could be readily identified on the basis of these characters thus assisting in the elucidation of epidemiological problems. On the basis of these characters the strains could be divided into six groups. Three of the groups corresponded to L. donovani s.l., L. major and L. aethiopica. The three other groups identified at present have no specific name associated with them.

摘要

对在埃塞俄比亚动物地理区域分离出的68株利什曼原虫测定了苹果酸脱氢酶(MDH)、葡萄糖磷酸异构酶(GPI)、6-磷酸葡萄糖脱氢酶(G6PGH)、6-磷酸葡萄糖酸脱氢酶(6PGDH)的电泳变异。测定的其他特征包括核DNA和动基体DNA的浮力密度以及分泌因子血清型。根据这些特征可以很容易地鉴定出这些菌株,从而有助于阐明流行病学问题。基于这些特征,这些菌株可分为六组。其中三组分别对应杜氏利什曼原虫复合种(L. donovani s.l.)、硕大利什曼原虫(L. major)和埃塞俄比亚利什曼原虫(L. aethiopica)。目前确定的另外三组没有与之相关的特定名称。

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