Ranta T, Stenman U H, Unnérus H A, Rossi J, Seppälä M
Obstet Gynecol. 1980 Apr;55(4):428-30.
Maternal plasma prolactin, estradiol-17 beta, and free estriol levels were estimated in 118 normal pregnancies and in 90 patients with preeclampsia at 35 to 40 weeks' gestation. In the preeclamptic patients, the prolactin values were similar to those of normal pregnancy; the levels were not affected by the severity of disease. At 37 to 38 weeks' gestation the maternal plasma free estriol levels correlated positively with the prolactin levels in preeclampsia (r = .313; P less than .05; N = 64). No correlation was found between the levels of prolactin and estradiol-17 beta or between prolactin and urinary estrogen. Fetal distress was related to decreased plasma estradiol levels, but this was not reflected in the prolactin concentrations. The results of the present study show that the estimation of plasma prolactin level is of no clinical significance in patients with preeclampsia.
在妊娠35至40周时，对118例正常妊娠孕妇和90例先兆子痫患者的母血催乳素、雌二醇-17β和游离雌三醇水平进行了测定。先兆子痫患者的催乳素值与正常妊娠者相似；其水平不受疾病严重程度的影响。在妊娠37至38周时，先兆子痫患者母血游离雌三醇水平与催乳素水平呈正相关（r = 0.313；P＜0.05；N = 64）。未发现催乳素水平与雌二醇-17β水平之间或催乳素与尿雌激素之间存在相关性。胎儿窘迫与血浆雌二醇水平降低有关，但这在催乳素浓度中未得到体现。本研究结果表明，测定先兆子痫患者的血浆催乳素水平无临床意义。
