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[免疫抗体所致牛贫血的实验研究。3. 贫血对肝脏的影响]

[Experimental study on cattle anemia due to immune antibodies. 3. Effects of anemia on the liver].

作者信息

Wujanz G, Rittenbach P, Seffner W, Dieffenbacher R

出版信息

Arch Exp Veterinarmed. 1978;32(5):775-80.

PMID:736720
Abstract

A characterisation in greater detail was undertaken of haemolytic anaemia caused by immune antibody and its effects on the liver of young cattle. Bioptate follow-up tests were applied to two animals, while bromosulphalein half-life and SGOT activity were determined in seven. Centrolobular liver necrosis was not reproducible. Some moderate liver cell damage was histologically detected. Certain responses recorded from the reticulohistiocytary part of the liver were interpreted as a consequence of aggravated damage to erythrocytes. The above moderate liver cell damage failed to produce statistically secured rises in bromosulphalein half-life nor SGOT activity.

摘要

对免疫抗体引起的溶血性贫血及其对幼牛肝脏的影响进行了更详细的表征。对两只动物进行了活检随访测试,同时对七只动物测定了溴磺酞半衰期和谷草转氨酶活性。小叶中心性肝坏死无法重现。组织学检测到一些中度肝细胞损伤。从肝脏的网状组织细胞部分记录到的某些反应被解释为红细胞损伤加重的结果。上述中度肝细胞损伤并未使溴磺酞半衰期或谷草转氨酶活性出现统计学上有意义的升高。

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