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肾小管性酸中毒:机制与管理

Renal tubular acidosis: mechanisms and management.

作者信息

Quintanilla A P

出版信息

Postgrad Med. 1980 Apr;67(4):60-73. doi: 10.1080/00325481.1980.11715423.

Abstract

Renal tubular acidosis is not one entity but several. Even though all its forms are characterized by the kidney's inability to excrete an appropriately acid urine, the mechanism of the defect, its laboratory and clinical manifestations, and its management vary considerably. One type can cause disabling complications in various organ systems, while another is generally asymptomatic. Differential diagnosis is straightforward, and treatment effective.

摘要

肾小管酸中毒并非单一疾病,而是多种疾病的统称。尽管其所有类型均表现为肾脏无法排出酸碱度适宜的尿液,但缺陷机制、实验室及临床表现以及治疗方法却大不相同。其中一种类型可在多个器官系统引发致残性并发症,而另一种通常无症状。鉴别诊断简单直接,治疗效果显著。

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