Clinical experience in neurosurgery with absele: a new absorbable haemostatic bone sealant.

Control of bleeding from the cut end of bone in neurosurgery is a necessity. In certain clinical situations, control of bleeding may be difficult because of the underlying pathology. Existing methods of control of haemorrhage with standard bone wax can interfere with subsequent healing. This paper presents the clinical results in 259 patients in whom a new absorbable bone sealant, Absele, has been used. Absele is a paste made from stabilised fibrin and soluble collagen and absorbs totally with minimal tissue reaction in approximately three weeks.