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长期吸入甲苯所致伴有弥漫性脑萎缩的平衡障碍

Equillibrium disorders with diffuse brain atrophy in long-term toluene sniffing.

作者信息

Sasa M, Igarashi S, Miyazaki T, Miyazaki K, Nakano S, Matsuoka I

出版信息

Arch Otorhinolaryngol. 1978 Oct 31;221(3):163-9. doi: 10.1007/BF01886291.

DOI:10.1007/BF01886291
PMID:736823
Abstract

A Japanese male who became habituated to sniffing toluene exhibited ataxia, tremor, incoordination and equilibrium disorders. There was pendular nystagmus with a normal caloric response. There were an inhibition of optokinetic nystagmus and a failure to follow over 0.1 Hz sine waves on eye tracking test. Angiogram and pneumoencephalogram revealed an atrophy of the midbrain and cerebrum, and degeneration of the cerebellum was suspected.

摘要

一名对嗅吸甲苯上瘾的日本男性出现了共济失调、震颤、不协调和平衡障碍。存在钟摆型眼球震颤,冷热试验反应正常。视动性眼球震颤受到抑制,在眼跟踪测试中无法跟踪超过0.1赫兹的正弦波。血管造影和气脑造影显示中脑和大脑萎缩,怀疑小脑有变性。

相似文献

1
Equillibrium disorders with diffuse brain atrophy in long-term toluene sniffing.长期吸入甲苯所致伴有弥漫性脑萎缩的平衡障碍
Arch Otorhinolaryngol. 1978 Oct 31;221(3):163-9. doi: 10.1007/BF01886291.
2
Encephalopathy due to toluene sniffing. Report of a case with magnetic resonance imaging.
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Pract Neurol. 2021 Oct;21(5):439-441. doi: 10.1136/practneurol-2021-002942. Epub 2021 May 26.
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Cerebral atrophy in young cannabis smokers.年轻大麻吸食者的脑萎缩
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Progressive optic neuropathy and sensorineural hearing loss due to chronic glue sniffing.慢性吸食胶水导致的进行性视神经病变和感音神经性听力损失。
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Acquired pendular nystagmus in toluene addiction.甲苯成瘾所致获得性钟摆型眼球震颤
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引用本文的文献

1
Auditory and vestibular functions after single or combined exposure to toluene: a review.单次或联合接触甲苯后的听觉和前庭功能:综述
Arch Toxicol. 1995;69(7):431-43. doi: 10.1007/s002040050196.
2
Persistent visual hallucinations secondary to chronic solvent encephalopathy: case report and review of the literature.慢性溶剂性脑病继发持续性视幻觉:病例报告及文献综述
J Neurol Neurosurg Psychiatry. 1983 Jan;46(1):83-6. doi: 10.1136/jnnp.46.1.83.
3
Solvent encephalopathy.溶剂性脑病

本文引用的文献

1
Toluene habituation. Report of a case.甲苯成瘾。一例报告。
N Engl J Med. 1963 Mar 28;268:719-21. doi: 10.1056/NEJM196303282681308.
2
Toluene sniffing producing cerebellar degeneration.吸入甲苯导致小脑变性。
Am J Psychiatry. 1961 Nov;118:461-2. doi: 10.1176/ajp.118.5.461.
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The effects of the organic solvents and industrial poisonings on the central nervous system.有机溶剂和工业中毒对中枢神经系统的影响。
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An introduction to the clinical toxicology of volatile substances.挥发性物质临床毒理学概论
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Permanent encephalopathy from toluene inhalation.吸入甲苯导致的永久性脑病。
N Engl J Med. 1966 Dec 29;275(26):1494-6. doi: 10.1056/NEJM196612292752608.
5
Petroleum hydrocarbon toxicity studies. XIII. Animal and human response to vapors of toluene concentrate.石油烃毒性研究。十三。动物和人类对甲苯浓缩物蒸气的反应。
Toxicol Appl Pharmacol. 1976 Jun;36(3):473-90. doi: 10.1016/0041-008x(76)90227-1.