Neurology Department, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
Neurology Department, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.
Pract Neurol. 2021 Oct;21(5):439-441. doi: 10.1136/practneurol-2021-002942. Epub 2021 May 26.
A 33-year-old man with a history of chronic toluene abuse through glue sniffing, developed tremors, cerebellar signs and cognitive decline. MR scan of the brain showed global cerebral and cerebellar atrophy with symmetrical T2-weighted hypointensities in the basal ganglia, thalami and midbrain. After stopping glue sniffing, his tremors, ataxia of gait, speech and cognition partially improved. Early recognition and intervention of toluene-induced leukodystrophy could prevent ongoing morbidity and premature mortality.
一位 33 岁男性，有慢性通过胶水嗅吸甲苯的滥用史，出现震颤、小脑体征和认知能力下降。脑部磁共振扫描显示大脑和小脑普遍萎缩，伴基底节、丘脑和中脑的对称性 T2 加权低信号。停止嗅吸胶水后，他的震颤、步态共济失调、言语和认知能力部分改善。早期识别和干预甲苯诱导的白质脑病可预防持续发病和过早死亡。
