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[不同年龄正常发育和交感神经切除小鼠的交感神经细胞轴突中缓慢转运蛋白迁移的放射自显影分析]

[Autoradiographic analysis of the migration of slowly translocating protein into the axons of sympathetic neurocytes of normally developing and sympathectomized mice of different ages].

作者信息

Iarygin V N, Lebedev L B

出版信息

Tsitologiia. 1980 Mar;22(3):350-4.

PMID:7368312
Abstract

Autoradiography was applied to a comparative analysis of transport dynamics of the newly synthesized protein into the axons of sympathetic neurocytes in mice of different age, developing both normally and after a partial desympathization by guanethidine. The data obtained make in possible to suppose that the rate of slowly transporting protein migration from perikaryons into axons is a little reduced in normal presenile mice. The lowest rate of migration of such proteins is discovered in neuron cells of the partially desympathized presenile mice.

摘要

应用放射自显影技术,对正常发育以及经胍乙啶部分去交感神经支配的不同年龄小鼠交感神经细胞轴突中新合成蛋白质的转运动力学进行比较分析。所得数据使我们有可能推测,在正常的老年前期小鼠中,从胞体缓慢转运至轴突的蛋白质迁移速率略有降低。在部分去交感神经支配的老年前期小鼠的神经细胞中,发现此类蛋白质的迁移速率最低。

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