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[从血液病患者红细胞中分离得到的血红素的色谱分析]

[Chromatographic analysis of the hemin isolated from the erythocytes of hematological patients].

作者信息

Bystrova I M, Manoĭlov Iu S

出版信息

Vopr Med Khim. 1980 Jan-Feb;26(1):97-9.

PMID:7368634
Abstract

Fractional composition of hemin, isolated from blood of patients with hematological impairments, differed from the composition characteristic for donors as shown by paper chromatography. Three fractions of hemin, which corresponded to various steps of polymerization of the substance, were found on chromatograms of donor hemin. Hemin from the patients were characterized by alteration both in amount and in the ratio of the fractions. Estimation of the hemin composition using paper chromatography might serve as an additional diagnostic test.

摘要

通过纸色谱法显示,从血液系统疾病患者血液中分离出的血红素的组分与献血者的组分特征不同。在献血者血红素的色谱图上发现了三个对应于该物质聚合不同阶段的血红素组分。患者的血红素在组分的数量和比例上均有改变。用纸色谱法估计血红素组分可作为一项辅助诊断测试。

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