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[饮食疗法对消化器官疾病肠道屏障状态的影响]

[Effect of diet therapy on the state of the intestinal barrier in digestive organ diseases].

作者信息

Chanturiia Zh A, Ekisenina N I

出版信息

Vopr Pitan. 1980 Mar-Apr(2):24-7.

PMID:7368669
Abstract

The effect of diets with varying amount of protein (135 and 160 g) on the intestinal barrier was studied in patients with the inadequate absorption syndrome of different etiology (chronic enterocolitis, the postgastroresection syndrome, chronic colitis). The data obtained indicate that in spite of the progress attained in the care of such patients at the present time, they show disturbed permeability of the intestinal barrier, determined by the passive hemagglutination test (PHAT) with diverse fractions of milk protein. With the postgastroresection syndrome, the abnormalities in the intestinal barrier arise less frequently, are less pronounced and more amenable by therapy as compared to patients with chronic enterocolitis. However, the condition of the small intestine should be taken into consideration in making dietetic recommendations for the patients suffering from the above diseases. The clinical findings and PHAT dynamics indicate that inclusion into the diet of over 135 g protein is not desirable.

摘要

研究了不同蛋白质含量(135克和160克)的饮食对不同病因(慢性小肠结肠炎、胃切除术后综合征、慢性结肠炎)吸收不良综合征患者肠道屏障的影响。所获数据表明,尽管目前对此类患者的护理已取得进展,但通过用不同乳蛋白组分进行的被动血凝试验(PHAT)测定,他们仍存在肠道屏障通透性紊乱的情况。与慢性小肠结肠炎患者相比,胃切除术后综合征患者肠道屏障异常出现的频率较低,程度较轻,且更易于治疗。然而,在为上述疾病患者制定饮食建议时,应考虑小肠的状况。临床发现和PHAT动态变化表明,饮食中蛋白质含量超过135克是不可取的。

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