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[新生大鼠早期发育阶段不同性质蛋白质的消化特性]

[Digestive characteristics of qualitatively different proteins in rats in the early postnatal development period].

作者信息

Stan E Ia, Smirnova L I, Chernikova L G, Chernikov M P

出版信息

Vopr Pitan. 1980 Mar-Apr(2):47-51.

PMID:7368674
Abstract

Starting from 15 days of age the rats were transferred to formula feeding with liquid diet adapted to the rat milk composition in terms of the main parameters. It was shown that caseine exclusion from the rat diet during the early postnatal period of the development and its replacement by proteins of milk serum or by bovine serum albumin that are not capable of curdling leads to a 2- and 3-fold increase, respectively in the protein evacuation rate from the stomach. As a result, the nitrogen content in the chyme of the small intestine rises. One may think that observed accumulation of protein proteolysis products indicates both considerable intensity of cavitary digestion of proteins qualitatively different from caseine in the small intestine of rats in the early postnatal period of the development and its functional overloading as a result of which the protein proteolysis products formed fail to be absorbed.

摘要

从15日龄开始,将大鼠转移至以适应大鼠乳成分主要参数的液体饮食进行配方喂养。结果表明,在出生后早期发育阶段,从大鼠饮食中排除酪蛋白,并分别用不能凝结的乳清蛋白或牛血清白蛋白替代,会导致胃中蛋白质排空率分别提高2倍和3倍。结果,小肠食糜中的氮含量升高。人们可能会认为,观察到的蛋白质水解产物积累表明,在出生后早期发育阶段,大鼠小肠中与酪蛋白性质不同的蛋白质腔消化强度相当大,并且其功能过载,导致形成的蛋白质水解产物无法被吸收。

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