Nikolaevskaia V R, Siviengsaĭ Ch, Chernikov M P
Vopr Pitan. 1985 Sep-Oct(5):26-9.
It has been established that during artificial feeding with milk substitute containing different protein components (casecite, bovine serum albumin, fibrinogen), the proximal-distal gradient of cavitary digestion of proteins is observed, with this gradient being more demonstrable as compared with natural feeding of postnatal animals. It has been shown that during experimental natural feeding, the proximal-distant gradient is observed in the distribution of acid proteinases in the small bowel, whereas during artificial feeding one can see a uniform distribution of acid proteinases in the proximal and distal parts of the small bowel. The activity of acid proteinases in the gastric mucosa of 18-day-old animals kept on natural feeding does not differ from the activity of these proteinases under artificial feeding with a substitute containing casecite as protein component. Artificial feeding with a substitute containing bovine serum albumin and fibrinogen as protein component entails a decrease in the activity of acid proteinases in the gastric mucosa.
已经确定，在用含有不同蛋白质成分（酪蛋白、牛血清白蛋白、纤维蛋白原）的代乳品进行人工喂养时，会观察到蛋白质腔消化的近端 - 远端梯度，与产后动物的自然喂养相比，这种梯度更明显。已经表明，在实验性自然喂养期间，在小肠中酸性蛋白酶的分布观察到近端 - 远端梯度，而在人工喂养期间，可以看到酸性蛋白酶在小肠近端和远端部分均匀分布。自然喂养的18日龄动物胃黏膜中酸性蛋白酶的活性与以含有酪蛋白作为蛋白质成分的代乳品进行人工喂养时这些蛋白酶的活性没有差异。以含有牛血清白蛋白和纤维蛋白原作为蛋白质成分的代乳品进行人工喂养会导致胃黏膜中酸性蛋白酶的活性降低。
