Faulkner J A, Niemeyer J H, Maxwell L C, White T P
Am J Physiol. 1980 Mar;238(3):C120-6. doi: 10.1152/ajpcell.1980.238.3.C120.
Following autologous transplantation of whole extensor digitorum longus (EDL) muscles of cats into the EDL site, we investigated the degree and time course of restoration of contractile properties of autografts toward control values. Isometric and isotonic contractile properties of 66 autografted EDL muscles were measured in situ from 40 to 440 days following transplantation. The control value for maximum tetanus tension (P0) was 27 N. The mean P0 for the autografts increased from 2% of control 40 days after transplantation to 26% 440 days after transplantation. When P0 was normalized per square centimeter of muscle fiber cross-sectional area, no significant difference was observed between the P0 of autografts (28 N/cm2) and controls. Compared to controls, autografts 40-179 days following transplantation had slower time to peak twitch tensions, half-relaxation times, and maximum velocities of shortening and smaller twitch-tetanus tension ratios. Between 180 and 440 days after transplantation, values for autografts approached control values. Autografts fatigued more than twice as rapidly as controls.
将猫的全趾长伸肌（EDL）进行自体移植到EDL部位后，我们研究了自体移植肌肉收缩特性恢复到对照值的程度和时间进程。在移植后40至440天，对66条自体移植的EDL肌肉的等长和等张收缩特性进行了原位测量。最大强直张力（P0）的对照值为27 N。自体移植肌肉的平均P0从移植后40天的对照值的2%增加到移植后440天的26%。当P0按每平方厘米肌肉纤维横截面积进行标准化时，自体移植肌肉的P0（28 N/cm²）与对照之间未观察到显著差异。与对照相比，移植后40 - 179天的自体移植肌肉达到峰值抽搐张力的时间、半松弛时间和最大缩短速度较慢，且抽搐 - 强直张力比值较小。在移植后180至440天之间，自体移植肌肉的值接近对照值。自体移植肌肉疲劳的速度比对照快两倍多。
