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精神分裂症的透析治疗:临床试验综述及对进一步研究的启示

Dialysis for schizophrenia: review of clinical trials and implications for further research.

作者信息

Fogelson D L, Marder S R, Van Putten T

出版信息

Am J Psychiatry. 1980 May;137(5):605-7. doi: 10.1176/ajp.137.5.605.

DOI:10.1176/ajp.137.5.605
PMID:7369409
Abstract

At least 67 schizophrenic patients have undergone dialysis for renal failure, without improvement in schizophrenic symptoms. Ninety-two nonuremic schizophrenic patients have received dialysis in nonblind studies; 22 improved, 21 improved partially, 47 showed no change, and 2 became worse. The authors point out factors other than dialysis that may affect outcome, including family respones and reduction in drug dose. They believe that until the results of current double-blind, sham-controlled trials are known, dialysis should not be prescribed as a treatment for schizophrenia.

摘要

至少67名精神分裂症患者因肾衰竭接受了透析治疗,但精神分裂症症状并无改善。92名非尿毒症精神分裂症患者在非盲法研究中接受了透析治疗;22名病情改善,21名部分改善,47名无变化,2名病情恶化。作者指出,除透析外可能影响治疗结果的因素,包括家庭反应和药物剂量减少。他们认为,在目前双盲、假对照试验的结果出来之前,不应将透析作为精神分裂症的一种治疗方法。

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Dialysis for schizophrenia: review of clinical trials and implications for further research.精神分裂症的透析治疗:临床试验综述及对进一步研究的启示
Am J Psychiatry. 1980 May;137(5):605-7. doi: 10.1176/ajp.137.5.605.
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Dialysis of schizophrenic patients: a double-blind study.
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