Oku Y, Katakura K, Kamiya M
Am J Trop Med Hyg. 1980 Mar;29(2):316-8. doi: 10.4269/ajtmh.1980.29.316.
Frogs and toads, as paratenic hosts, are known to be sources of human angiostrongyliasis. The present investigation was carried out to examine the role of the tadpole as an experimental intermediate host. First-, second-, and third-stage larvae were found in tadpoles of Xenopus laevis from the 1st, 14th, and 18th days, respectively, after exposure to the first-stage larva of Angiostrongylus cantonensis. Third-stage larvae collected from a frog which had metamorphosed from an exposed tadpole reached maturity and oviposited in an albino rat. This is the first demonstration that a vertebrate, the tadpole of X. laevis, can serve as an experimental intermediate host of A. cantonensis.
青蛙和蟾蜍作为转续宿主，已知是人类广州管圆线虫病的传染源。本研究旨在检验蝌蚪作为实验中间宿主的作用。在暴露于广州管圆线虫第一期幼虫后，分别于第1天、第14天和第18天在非洲爪蟾蝌蚪中发现了第一期、第二期和第三期幼虫。从暴露蝌蚪变态而成的青蛙体内收集的第三期幼虫发育成熟并在白化大鼠体内产卵。这首次证明了脊椎动物——非洲爪蟾蝌蚪——可作为广州管圆线虫的实验中间宿主。
