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Biochemical basis for the resistance of guinea pigs to carcinogenesis by 2-acetylaminofluorene.

作者信息

Kawajiri K, Yonekawa H, Hara E, Tagashira Y

出版信息

Biochem Biophys Res Commun. 1978 Dec 14;85(3):959-65. doi: 10.1016/0006-291x(78)90637-x.

DOI:10.1016/0006-291x(78)90637-x
PMID:736968
Abstract
摘要

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1
Biochemical basis for the resistance of guinea pigs to carcinogenesis by 2-acetylaminofluorene.豚鼠对2-乙酰氨基芴致癌作用具有抗性的生化基础。
Biochem Biophys Res Commun. 1978 Dec 14;85(3):959-65. doi: 10.1016/0006-291x(78)90637-x.
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Genetic differences in 2-acetylaminofluorene mutagenicity in vitro associated with mouse hepatic aryl hydrocarbon hydroxylase activity induced by polycyclic aromatic compounds.
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Microsomal N-hydroxylase modification as a first step in carcinogenesis by arylamines [proceedings].微粒体N-羟化酶修饰作为芳胺致癌作用的第一步[会议论文集]
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In vitro metabolism and mutagenic activation of 2-acetylaminofluorene by subcellular liver fractions from Cotton rats.
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[Microsomal oxygenase enzyme system during chronic administration of 2-acetylaminofluorene].[2-乙酰氨基芴长期给药过程中的微粒体加氧酶系统]
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A relative deficiency of cytochrome P-450 and aryl hydrocarbon [benzo(a)pyrene] hydroxylase in hyperplastic nodules induced by 2-acetylaminofluorene in rat liver.大鼠肝脏中2-乙酰氨基芴诱导的增生性结节中细胞色素P-450和芳烃[苯并(a)芘]羟化酶的相对缺乏。
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Induction, activation, and inhibition of hamster and rat liver microsomal arylamide and arylamine N-hydroxylase.仓鼠和大鼠肝脏微粒体芳酰胺及芳胺N-羟化酶的诱导、激活与抑制
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Developmental pattern of 3-methylcholanthrene-inducible mutagenic activation of N-2-fluorenylacetamide, 2-fluorenamine, and 2,4-diaminoanisole in the rabbit.3-甲基胆蒽诱导的兔体内N-2-芴基乙酰胺、2-芴胺和2,4-二氨基苯甲醚诱变激活的发育模式
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Genetic differences in the enzymic properties of the aromatic hydrocarbon inducible N-hydroxylation of 2-acetylaminofluorene in mouse liver.
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