Ecker A
Ann Neurol. 1980 Feb;7(2):181-2. doi: 10.1002/ana.410070214.
Fifty-eight patients who had been relieved of tic douloureux (TD) for least 3 years after partial destruction of the trigeminal sensory root by injection of minimal amounts of alcohol were reexamined 3 1/2 to 21 years after treatment. Of 41 patients still in remission at a median of 10 years after treatment, 32 had analgesia; i.e., sensation of pain from pinprick was absent in all 52 originally neuralgic areas. The other 9 patients in remission had some pain on pinprick in their neuralgic areas. In contrast, of 17 patients with recurrence of TD 3 1/2 to 11 years (median, 6 years) after treatment, at least 15 had demonstrable pain on pinprick in the neuralgic areas. It is concluded that continuing absence of pain on pinprick in the affected facial mucocutaneous area (or areas) is associated with prolonged relief of tic douloureux.
58例患者在通过注射少量酒精对三叉神经感觉根进行部分破坏后，已缓解三叉神经痛（TD）至少3年，在治疗后3.5至21年进行了复查。在治疗后中位时间为10年仍处于缓解期的41例患者中，32例有镇痛效果；也就是说，在所有52个最初的神经痛区域均无针刺疼痛感觉。其余9例缓解期患者的神经痛区域在针刺时有一些疼痛。相比之下，在治疗后3.5至11年（中位时间为6年）出现TD复发的17例患者中，至少15例在神经痛区域针刺时有明显疼痛。得出的结论是，受累面部黏膜皮肤区域持续无针刺疼痛与三叉神经痛的长期缓解相关。
