Hall J E, Mills S E, Carey R M
Atherosclerosis. 1980 Jan;35(1):87-92. doi: 10.1016/0021-9150(80)90030-1.
Virgin male Sprague-Dawley rats are resistant to atheroma formation. An adrenal homogenate from such rats delayed the increase in serum cholesterol concentrations in cholesterol-fed New Zealand white rabbits. More importantly, aortic atherosclerosis was markedly reduced when compared to a similar population fed cholesterol without adrenal homogenate for 14 weeks. The nature of the active constituent in this homogenate and its mode of action are unknown.
未交配的雄性斯普拉格-道利大鼠对动脉粥样硬化的形成具有抗性。来自此类大鼠的肾上腺匀浆可延缓喂食胆固醇的新西兰白兔血清胆固醇浓度的升高。更重要的是，与在14周内喂食胆固醇但未添加肾上腺匀浆的类似群体相比，主动脉粥样硬化明显减轻。这种匀浆中活性成分的性质及其作用方式尚不清楚。
