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使用铁强化食盐(氯化钠)防治贫血:一项初步研究的结果

The use of common salt (sodium chloride) fortified with iron to control anaemia: results of a preliminary study.

作者信息

Nadiger H A, Krishnamachari K A, Naidu A N, Rao B S, Srikantia S G

出版信息

Br J Nutr. 1980 Jan;43(1):45-51. doi: 10.1079/bjn19800063.

DOI:10.1079/bjn19800063
PMID:7370217
Abstract
  1. Iron-deficiency anaemia continues to be a major public health problem in all developing countries. Fortification of commonly consumed food items has been suggested as an effective method of preventing anaemia. Common salt (sodium chloride) has been identified as a suitable vehicle to be fortified with Fe in India. 2. Common salt was fortified with ferric orthophosphate (3500 mg/kg) and sodium hydrogen sulphate (5000 mg/kg) to provide an additional 1 mg elemental Fe/g common salt consumed. 3. After ascertaining the acceptability of the fortified salt with respect to its colour, taste and bioavailability a pilot feeding trial was conducted among residential schoolchildren in Hyderabad. Feeding of the fortified salt for a period of 1 year resulted in a significant increase in the haemoglobin level of these children. There was also a significant reduction in the prevalence of anaemia among children given the fortified salt. 4. Before the same fortified salt is recommended as a public health measure to prevent Fe-deficiency anaemia among our population it is necessary that further large-scale community trials with this fortified salt are carried out particularly among the rural population.
摘要
  1. 缺铁性贫血在所有发展中国家仍然是一个主要的公共卫生问题。对常见食品进行强化已被认为是预防贫血的有效方法。在印度,食盐(氯化钠)已被确定为适合强化铁的载体。2. 用正磷酸铁(3500毫克/千克)和硫酸氢钠(5000毫克/千克)对食盐进行强化,以便每摄入1克食盐能额外提供1毫克元素铁。3. 在确定强化盐在颜色、味道和生物利用度方面的可接受性之后,在海得拉巴的寄宿学童中进行了一项试点喂养试验。喂养强化盐1年导致这些儿童的血红蛋白水平显著提高。食用强化盐的儿童中贫血患病率也显著降低。4. 在将同样的强化盐作为预防我国人群缺铁性贫血的公共卫生措施推荐之前,有必要对这种强化盐进行进一步的大规模社区试验,特别是在农村人口中进行。

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