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[癌细胞中的温度相变]

[Temperature phase transitions in cancer cells].

作者信息

Popov G A, Polivoda B I, Konev V V

出版信息

Biofizika. 1980 Jan-Feb;25(1):177-8.

PMID:7370323
Abstract

Light scattering (90 degrees) of Ehrlich ascites tumor and sarcoma 37 cell suspension in the temperature range 25-60 degrees C was studied (heating velocity was 3 grad/min). It is found that the scattering curve has the peak at 46 degrees C and two plots which are typical of phase transitions in the membranes; the first plot in the range 40-46 degrees C is reversible and the second one at 46-51 degrees C is irreversible. It is proposed that 46 degrees is a critical temperature for the membranes structure stability and viability of the studied cells.

摘要

研究了艾氏腹水瘤和肉瘤37细胞悬液在25至60摄氏度温度范围内的光散射(90度)情况(升温速率为每分钟3摄氏度)。发现散射曲线在46摄氏度处有一个峰值,并且有两条典型的膜相变曲线;40至46摄氏度范围内的第一条曲线是可逆的,46至51摄氏度范围内的第二条曲线是不可逆的。有人提出,46摄氏度是所研究细胞的膜结构稳定性和活力的临界温度。

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