Debov S S, Fedotov V P, Khoroshutina E B, Aleshina I V, Andrianova L E
Biull Eksp Biol Med. 1980 Feb;89(2):162-3.
Hypophysectomy in rats is accompanied by a significant rise in PNPase activity in ribosomal fractions of the liver. Injection of growth hormone into operated animals produces inhibition of PNPase activity. The linear dependence "dose-response" was recorded with the use of a dosage range of 5 to 100 micrograms/animal. The action of growth hormone was most pronounced 18 hours following its single injection.
大鼠垂体切除术后，肝脏核糖体组分中的PNP酶活性显著升高。给手术动物注射生长激素可抑制PNP酶活性。使用5至100微克/动物的剂量范围记录到了“剂量-反应”的线性相关性。生长激素单次注射后18小时作用最为明显。
