[Importance of the growth hormone in regulating polynucleotide phosphorylase activity in the rat liver].

Hypophysectomy in rats is accompanied by a significant rise in PNPase activity in ribosomal fractions of the liver. Injection of growth hormone into operated animals produces inhibition of PNPase activity. The linear dependence "dose-response" was recorded with the use of a dosage range of 5 to 100 micrograms/animal. The action of growth hormone was most pronounced 18 hours following its single injection.