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计算机断层扫描用于测定原发性血色素沉着症中的肝脏铁含量。

Computed tomography for determining liver iron content in primary haemochromatosis.

作者信息

Chapman R W, Williams G, Bydder G, Dick R, Sherlock S, Kreel L

出版信息

Br Med J. 1980 Feb 16;280(6212):440-2. doi: 10.1136/bmj.280.6212.440.

Abstract

Dual-energy computed tomography (CT) was used to estimate hepatic iron concentration in eight patients with primary haemochromatosis with varying degrees of iron overload. The values corresponded closely with these derived from chemical analysis of liver tissue obtained by biopsy (correlation coefficient 0.993). Dual-energy CT therefore seems to provide an accurate and non-invasive alternative to liver biopsy as a means of measuring liver iron concentration in patients with primary haemochromatosis and possibly other iron overload states.

摘要

双能计算机断层扫描(CT)用于估计8例不同程度铁过载的原发性血色素沉着症患者的肝脏铁浓度。这些值与通过活检获得的肝组织化学分析结果密切相关(相关系数0.993)。因此,双能CT似乎为肝活检提供了一种准确且无创的替代方法,可作为测量原发性血色素沉着症患者以及可能其他铁过载状态患者肝脏铁浓度的手段。

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本文引用的文献

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Measurement of liver-iron concentration in needle-biopsy specimens.
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