Identification of embryonic motoneurons in vitro: their survival is dependent on skeletal muscle.
作者信息
Bennett M R, Lai K, Nurcombe V
出版信息
Brain Res. 1980 May 26;190(2):537-42. doi: 10.1016/0006-8993(80)90295-4.
PMID:7370805
Abstract
摘要
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Identification of embryonic motoneurons in vitro: their survival is dependent on skeletal muscle.体外胚胎运动神经元的鉴定：它们的存活依赖于骨骼肌。
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Neuronal dropout is greater in hindlimb motor nuclei than in forelimb motor nuclei in aged rats.在老年大鼠中，后肢运动核团的神经元缺失比前肢运动核团更严重。
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Muscle derived motoneuron trophic factors promote the survival of motoneurons in vitro only when serum is present in the growth medium.仅当生长培养基中存在血清时，肌肉衍生的运动神经元营养因子才能在体外促进运动神经元的存活。
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Promoting and directing axon outgrowth.促进并引导轴突生长。
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Neurite outgrowth from embryonic chicken spinal neurons is promoted by media conditioned by muscle cells.来自肌肉细胞的条件培养基可促进胚胎鸡脊髓神经元的神经突生长。
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Embryonic chick retinal ganglion cells identified "in vitro". Their survival is dependent on a factor from the optic tectum.体外鉴定的胚胎期鸡视网膜神经节细胞。它们的存活依赖于来自视顶盖的一种因子。
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Trophic effects of skeletal muscle extracts on ventral spinal cord neurons in vitro: separation of a protein with morphologic activity from proteins with cholinergic activity.骨骼肌提取物对体外培养的脊髓腹侧神经元的营养作用：具有形态学活性的蛋白质与具有胆碱能活性的蛋白质的分离。
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Activity and synapse elimination at the neuromuscular junction.神经肌肉接头处的活动与突触消除
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Fluorescent carbocyanine dyes allow living neurons of identified origin to be studied in long-term cultures.荧光碳菁染料可用于在长期培养中研究已确定来源的活神经元。
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