连续骨扫描在评估晚期乳腺癌化疗反应中的预测价值。
The predictive value of serial bone scans in assessing response to chemotherapy in advanced breast cancer.
作者信息
Bitran J D, Bekerman C, Desser R K
出版信息
Cancer. 1980 Apr 1;45(7):1562-8. doi: 10.1002/1097-0142(19800401)45:7<1562::aid-cncr2820450709>3.0.co;2-g.
A retrospective analysis was made of 25 patients with breast cancer treated only with chemotherapy in order to determine the predictive value of technetium-99m bone scanning in determining response to chemotherapy. Whole-body scanning demonstrated bone healing in only 3 of 25 patients. However, the presence of stable disease on bone scan correlated with a good prognosis as 12 patients with stable scans had a significantly longer survival time than did the 13 patients who showed progression on scans (17.7 and 7.8 months, respectively P less than 0.01 greater than 0.005, Wilcoxan). Our analysis indicates that bone scans are a relatively crude technique for monitoring response to chemotherapy in patients with breast cancer.
对仅接受化疗的25例乳腺癌患者进行回顾性分析，以确定锝-99m骨扫描在判定化疗反应方面的预测价值。全身扫描显示，25例患者中仅有3例出现骨愈合。然而，骨扫描显示病情稳定与预后良好相关，因为12例扫描结果稳定的患者生存时间明显长于13例扫描显示病情进展的患者（分别为17.7个月和7.8个月，Wilcoxan检验，P小于0.01大于0.005）。我们的分析表明，骨扫描是监测乳腺癌患者化疗反应的一种相对粗略的技术。
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