醋酸叔丁酯泼尼松龙诱导大鼠肾多囊症
Renal polycystosis in the rat induced by prednisolone tertiary butyl acetate.
作者信息
Whitehouse R W, Lendon R G, Lendon M
出版信息
Experientia. 1980 Feb 15;36(2):244-5. doi: 10.1007/BF01953758.
PMID:7371773
Abstract
A single i.m. injection of 66 mg/kg prednisolone tertiary butyl acetate given on the 1st day of life produced glomerular degeneration and collecting duct and proximal tubule cysts in rat kidneys. There was evidence of delayed nephrogenesis leading to persistance of the neogenic zone.
摘要
出生第一天单次肌肉注射66毫克/千克的醋酸叔丁酯泼尼松龙会导致大鼠肾脏出现肾小球变性、集合管和近端肾小管囊肿。有证据表明肾发生延迟，导致新生区持续存在。
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