Dulout F N, Larramendy M L, Olivero O A
Experientia. 1980 Mar 15;36(3):346-7. doi: 10.1007/BF01952318.
Treatment of BHK cells for 8 h with triethylenemelamine (TEM) followed by caffeine for 4 or 8 h, increased the frequency of anaphase-telophase chromatin bridges in relation to controls and TEM-treated cells. These results indicate that TEM-induced chromosome lesions detected as chromatin bridges at anaphase-telophase could be potentiated by caffeine.
用三亚乙基三聚氰胺(TEM)处理BHK细胞8小时,随后用咖啡因处理4或8小时,与对照组和仅用TEM处理的细胞相比,后期-末期染色质桥的频率增加。这些结果表明,在后期-末期被检测为染色质桥的TEM诱导的染色体损伤可能会被咖啡因增强。