Bhatti R A, Ablin R J, Zamora S, Totonchi E, Bush I M, Guinan P D
Experientia. 1980 Mar 15;36(3):349-50. doi: 10.1007/BF01952320.
The 'arming' of normal peripheral blood leukocytes (PBL) by cytophilic antibody in the sera of prostatic cancer patients is suppressed by pretreatment of PBL with normal human seminal plasma (HuSPl). Suppression of cytophilic antibody by HuSPl extends the spectrum of immunologic reactions on which SPl has an immunosuppressive effect and may provide further insight into the possible role of SPl in the natural history of prostatic cancer.
前列腺癌患者血清中的嗜细胞抗体对正常外周血白细胞(PBL)的“武装”作用,会被正常人精浆(HuSPl)预处理PBL所抑制。HuSPl对嗜细胞抗体的抑制作用扩展了精浆具有免疫抑制作用的免疫反应谱,并且可能为深入了解精浆在前列腺癌自然病程中的潜在作用提供更多线索。