Harcus A W, Ward A E, Smith D W
J Int Med Res. 1980;8(2):153-5. doi: 10.1177/030006058000800210.
Temgesic Injection (buprenorphine), a potent analgesic agent, was given to 240 patients under 18 years of age during a year of monitored release. All but four had the product for the management of moderate or severe pain in the immediate post-operative period. Analgesia was reported as adequate or good in 90% of these young patients when it was assessed 2 and 4 hours after infection. There were no reports of side-effects commonly associated with strong analgesics and particularly antagonist-analgesics such as confusion, hallucination, blurred vision, dry mouth and lightheadedness. There were no serious respiratory or cardiovascular effects. The incidences of other events did not differ from those recorded in the much larger adult population of almost 8,000 patients. Buprenorphine is an effective analgesic suitable for use in the young post-operative patient.
丁丙诺啡注射液(丁丙诺啡)是一种强效镇痛剂,在一年的监测期内给予了240名18岁以下的患者。除4人外,其余患者均使用该产品用于术后即刻中度或重度疼痛的管理。在感染后2小时和4小时进行评估时,90%的这些年轻患者报告镇痛效果良好或足够。没有关于与强效镇痛药尤其是拮抗镇痛药相关的常见副作用的报告,如意识模糊、幻觉、视力模糊、口干和头晕。没有严重的呼吸或心血管影响。其他事件的发生率与近8000名成年患者的记录没有差异。丁丙诺啡是一种有效的镇痛药,适用于年轻的术后患者。