体外老化对培养的人皮肤成纤维细胞中可饱和及不饱和糖摄取影响的研究。
Studies on the effects of in vitro ageing on saturable and nonsaturable sugar uptake in cultured human skin fibroblasts.
作者信息
Germinario R J, Oliveira M, Taylor M
出版信息
Gerontology. 1980;26(4):181-7. doi: 10.1159/000212413.
PMID:7372098
Abstract
The Vmax for saturable (i.e. 2-deoxy-D-glucose) sugar transport in cultured human fibroblasts was found to increase with in vitro ageing when the results were expressed per 10(6) cells. No age-related changes were observed in the Km for 2-deoxy-D-glucose transport or in nonsaturable (i.e. L-glucose) sugar uptake.
摘要
当以每10⁶个细胞来表示结果时，发现培养的人成纤维细胞中可饱和（即2-脱氧-D-葡萄糖）糖转运的最大速度（Vmax）会随着体外老化而增加。在2-脱氧-D-葡萄糖转运的米氏常数（Km）或非饱和（即L-葡萄糖）糖摄取方面未观察到与年龄相关的变化。
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