阿尔茨海默病患者大脑中的铝含量。
Aluminum levels in brain in Alzheimer's disease.
作者信息
Trapp G A, Miner G D, Zimmerman R L, Mastri A R, Heston L L
出版信息
Biol Psychiatry. 1978 Dec;13(6):709-18.
PMID:737258
Abstract
In both human Alzheimer's disease and aluminum encephalopathy of animals, changes are observed in neurofibrillary structures. We have found that brains from Alzheimer patients contain approximately 1.4 times the aluminum level found in a control series. Some possible methodological problems are discussed. We have proposed a plausible chemical mechanism for the changes of aluminum encephalopathy.
摘要
在人类阿尔茨海默病和动物铝性脑病中，均可观察到神经纤维结构的变化。我们发现，阿尔茨海默病患者大脑中的铝含量约为对照组的1.4倍。文中讨论了一些可能存在的方法学问题。我们提出了一种关于铝性脑病变化的合理化学机制。
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