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雏鸡营养性脑病愈合阶段的基底膜迷路

Basal membrane labyrinths in the healing stages of chick nutritional encephalopathy.

作者信息

Sandbank U, Bubis J J, Bartov I, Dror I, Budowski P, Wolman M

出版信息

Neuropathol Appl Neurobiol. 1980 Jan-Feb;6(1):3-8. doi: 10.1111/j.1365-2990.1980.tb00198.x.

DOI:10.1111/j.1365-2990.1980.tb00198.x
PMID:7374910
Abstract

Chicks were fed a diet rich in oxidized oil and deficient in alpha-tocopherol. As soon as nutritional encephalopathy developed the animals were immediately put on to a normal diet, and kept alive for up to 166 days. Examination of the cerebellum showed multiple foci of healed encephalomalacia with EM appearance of basal membrane labyrinths between astroglial cells and around blood vessels. The possible origin of the basement membrane material in this conditions was considered and compared with similar formations in normal animals, in CNS tumour explants, and after portocaval anastomosis as well as after spinal cord lesions.

摘要

给雏鸡喂食富含氧化油且缺乏α-生育酚的饲料。一旦出现营养性脑病,动物立即改为正常饮食,并存活长达166天。对小脑的检查显示有多个愈合的脑软化灶,电镜下可见星形胶质细胞之间和血管周围有基底膜迷路的表现。研究了这种情况下基底膜物质的可能来源,并与正常动物、中枢神经系统肿瘤外植体、门腔静脉吻合术后以及脊髓损伤后的类似结构进行了比较。

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