Surina M N
Probl Endokrinol (Mosk). 1980 Mar-Apr;26(2):41-5.
Morphological changes in the testis of human fetuses (period of embryogenesis--from 8 to 28 weeks) during their differentiation were studied by histological and morphological methods. Investigations carried out demonstrated that complete cycle of transformation in the intestitial and embryonic tissue of the fetal testis could be divided into two main periods: the first period was attended by a gradual increase in the count and differentiation of Heydig's cells in the interstitial tissue (from the 8th to the 12th week of embryogenesis); gradual involution of Leydig's cells in the interstitial tissue and development of seminiferous tubules prevailed during the second period (from the 15th to the 28th week of embryogenesis). In the course of prenatal development of the human fetus testis Leydig's cells passed through a number of successive stages, each one being characterized by a definite functional activity level of these cells. The detected changes in the testes were apparently connected both with the changes in the Leydig's cells count and their functional activity, and with progressive growth of the tubules.
采用组织学和形态学方法，研究了人类胎儿睾丸（胚胎发生期——8至28周）在分化过程中的形态学变化。所开展的研究表明，胎儿睾丸间质和胚胎组织的完整转化周期可分为两个主要阶段：第一阶段，间质组织中睾丸间质细胞数量逐渐增加并分化（胚胎发生第8至12周）；第二阶段，间质组织中睾丸间质细胞逐渐退化，同时生精小管发育占主导（胚胎发生第15至28周）。在人类胎儿睾丸的产前发育过程中，睾丸间质细胞经历了一系列连续阶段，每个阶段这些细胞都具有特定的功能活性水平。检测到的睾丸变化显然与睾丸间质细胞数量及其功能活性的变化以及小管的渐进性生长有关。
