Edery M, Carreau S, Drosdowsky A
Steroids. 1980 Apr;35(4):381-8. doi: 10.1016/0039-128x(80)90139-7.
Adrenal gland homogenates from four different strains of mice were incubated with (4-14C)-pregnenolone and a NADPH generating system. Although quantitative differences between high and low mammary tumor strains occured, all mice synthesized estrone. The highest aromatase activity was found 2 months after castration of the (C3H x RIII) F1 mice when castration was performed at 4 days of age; this activity was lower in the C3H mice and almost negligible in the RIII and C57BL mice.
将来自四种不同品系小鼠的肾上腺匀浆与（4-¹⁴C）-孕烯醇酮及一个烟酰胺腺嘌呤二核苷酸磷酸（NADPH）生成系统一起孵育。尽管高乳腺肿瘤品系和低乳腺肿瘤品系之间存在数量差异，但所有小鼠均合成了雌酮。当在4日龄时对（C3H×RIII）F1小鼠进行去势，在去势后2个月发现其芳香化酶活性最高；C3H小鼠的这种活性较低，而在RIII和C57BL小鼠中几乎可以忽略不计。
