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[不同磷脂含量日粮对大鼠肝脏磷酸化酶A1和A2及胆固醇酯酶活性的影响]

[Effect of rations with a varying phospholipid content on rat liver phosphorylase A1 and A2 and cholesterol esterase activity].

作者信息

Zviagina O P, Nesterin M F

出版信息

Vopr Pitan. 1980 Jan-Feb(1):52-4.

PMID:7376555
Abstract

The effect of varied amounts of phospholipids in the diet (100, 30 and 0.5% of the total lipid content) on the lipid composition and activity of lysosomal phospholipases A1 and A2 and cholesterinesterase of the rat liver was studied. The experiment lasted 24 days. The liver weight increased in both groups of animals under test, no differences in the content of total lipids being found. Variations in the activity of lipolytic enzymes were of different directions. The animals given pure phospholipids demonstrated less activity of phospholipase A1 without changes in phospholipase A2 activity, a tendency towards elevated activity of cholesterinesterase and drop in the content of phospholipids in the liver. The animals fed 30% of phospholipids showed higher activity of phospholipases A1 and A2, reduced activity of cholesterinesterase as well as decreased protein content in the liver.

摘要

研究了饮食中不同含量的磷脂(占总脂质含量的100%、30%和0.5%)对大鼠肝脏脂质组成、溶酶体磷脂酶A1和A2以及胆固醇酯酶活性的影响。实验持续24天。受试的两组动物肝脏重量均增加,总脂质含量未发现差异。脂解酶活性的变化方向不同。给予纯磷脂的动物表现出磷脂酶A1活性较低,磷脂酶A2活性无变化,胆固醇酯酶活性有升高趋势,肝脏中磷脂含量下降。喂食30%磷脂的动物表现出磷脂酶A1和A2活性较高,胆固醇酯酶活性降低,肝脏中蛋白质含量也降低。

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Vopr Pitan. 1980 Jan-Feb(1):52-4.
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