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[微生物中的类固醇转化酶。 XIII. 诺卡氏菌中类固醇结构与4-烯-3-氧代类固醇:(受体)-1-烯氧化还原酶诱导之间的关系]

[Steroid transforming enzymes in microorganisms. XIII. Relationship between steroid structure and induction of 4-ene-3-oxosteroid: (acceptor)-1-ene-oxidoreductase in Nocardia opaca].

作者信息

Hörhold C, Hüller E, Rose G

出版信息

Z Allg Mikrobiol. 1980;20(1):23-32. doi: 10.1002/jobm.19800200104.

DOI:10.1002/jobm.19800200104
PMID:7376687
Abstract

The induction of the 4-ene-3-oxosteroid: (acceptor)-1-ene-oxidoreductase in Nocardia opaca has been shown to be dependent on both hydrophilic and hydrophobic structural features of the steroid molecule, i.g. the nature of the oxygen function in positions 11 and 20 and the presence of the methyl group in position 10 influence the induction of the enzyme drastically. In this connection the metabolism of the steroid inductors being degradated during the induction process has been considered.

摘要

在不透明诺卡氏菌中,4-烯-3-氧代甾体:(受体)-1-烯氧化还原酶的诱导已被证明取决于甾体分子的亲水性和疏水性结构特征,例如11位和20位氧官能团的性质以及10位甲基的存在对该酶的诱导有极大影响。在此方面,已考虑了在诱导过程中被降解的甾体诱导剂的代谢情况。

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[Steroid-transforming enzymes from microorganisms. XII. Induction characteristics of the 4-en-3-oxosteroid: (acceptor)-1-en-oxidoreductase in Nocardia opaca].
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[Steroid conjugating enzyme from microorganisms. VI. Purification of 4-en-o-oxosteroid: (acceptor)-1-en-oxidoreductase from Nocardia opaca by affinity chromatography].[来自微生物的类固醇结合酶。VI. 通过亲和色谱法从不透明诺卡氏菌中纯化4-烯-o-氧代类固醇:(受体)-1-烯氧化还原酶]
J Steroid Biochem. 1977 Sep;8(9):1017-24. doi: 10.1016/0022-4731(77)90201-1.
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[Steroid-transforming enzymes from microorganisms. II. Purification of a 3-oxosteroid: (2,6-dichlorophenolindophenol) delta 1-oxidoreductase from Nocardia opaca by means of affinity chromatography].
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