Carlsson A S, Magnusson B, Möller H
Acta Orthop Scand. 1980 Feb;51(1):57-62. doi: 10.3109/17453678008990769.
Out of 134 patients patch tested after total hip replacement (metal-to-plastic) 13 were sensitive to one or two of the implanted metals. In a prospective series of 112 patients, nine were sensitive to nickel before and another three developed sensitivity to nickel or cobalt after the arthroplasty. In the retrospective as well as in the prospective series the complications could in all cases but one be explained on grounds other than allergy. The incidence of contact allergy to nickel before a planned arthroplasty was 12 per cent in females and 4 per cent in males. It is doubtful whether metal sensitivity could be induced by a total hip arthroplasty. However, in cases of a preexisting metal allergy, a certain degree of caution is recommended.
在134例行全髋关节置换术（金属对塑料）后接受斑贴试验的患者中，有13例对一种或两种植入金属敏感。在一项针对112例患者的前瞻性研究中，9例患者术前对镍敏感，另有3例患者在关节置换术后对镍或钴产生敏感性。在回顾性研究和前瞻性研究中，除1例之外，所有病例的并发症都可以用过敏以外的原因来解释。计划进行关节置换术前，女性对镍接触过敏的发生率为12%，男性为4%。全髋关节置换术是否会诱发金属敏感性尚不确定。然而，对于已有金属过敏的病例，建议保持一定程度的谨慎。
