Kristensen J K, Henriksen O
Acta Physiol Scand. 1980 Jan;108(1):1-6. doi: 10.1111/j.1748-1716.1980.tb06493.x.
The influence of duration of vascular occlusion upon the reactive hyperemic response in human cutaneous tissue was studied in 6 subjects. Blood flow in cutaneous tissue was measured dorsally on the distal phalanx of the second finger by the local 133Xenon washout technique. Post-occlusive blood flow, calculated from the steepest part of the 133Xenon washout curve just after release of vascular occlusion, reached a maximum value when duration of vascular occlusion was 12 min. However, excess cumulative blood flow, i.e. the integrated blood flow during reactive hyperemia minus integrated pre-ischemic blood flow for a period corresponding to the duration of the reactive hyperemic response, increased with increasing duration of vascular occlusion from 3 to 24 min. Fractional repayment, i.e. excess cumulative blood flow divided by pre-ischemic blood flow times duration of vascular occlusion, was not correlated significantly to duration of vascular occlusion. However, there was a significant inverse correlation between fractional repayment and pre-occlusive blood flow, indicating that, besides metabolic factors, pre-ischemic blood flow in cutaneous tissue is influenced by other factors, such as heat regulation.
在6名受试者中研究了血管闭塞持续时间对人体皮肤组织反应性充血反应的影响。采用局部133氙洗脱技术，在右手食指末节背侧测量皮肤组织血流。血管闭塞解除后，根据133氙洗脱曲线最陡部分计算的闭塞后血流，在血管闭塞持续时间为12分钟时达到最大值。然而，过量累积血流量，即反应性充血期间的积分血流量减去与反应性充血反应持续时间相对应的一段时间内的缺血前积分血流量，随着血管闭塞持续时间从3分钟增加到24分钟而增加。分数偿还，即过量累积血流量除以缺血前血流量乘以血管闭塞持续时间，与血管闭塞持续时间无显著相关性。然而，分数偿还与闭塞前血流量之间存在显著负相关，表明除代谢因素外，皮肤组织的缺血前血流量还受其他因素影响，如热调节。
