Birkin A A
Arkh Patol. 1980;42(1):10-7.
The results of immunomorphological examinations of the pulmonary tissue of rabbits under conditions of immunisation, intratracheal insertion of capron thread and combinations thereof are described. In all the instances bronchovascular and alveolovascular barriers of the lungs were disturbed leading to the development of alterative, exudative, and proliferative lesions. Inflammatory lesions developed with participation of humoral and cellular immune processes including immunopathologic reactions: immunocomplex damage of the tissue and probably hypersensitivity of the delayed type. The features of the investigated variants of pneumonia are associated with different ways of antigen penetration into the lungs and, evidently, with quantitative and qualitative features of the latter. The role of immunization in the pathogenesis of inflammatory lung diseases consists in the antiinflammatory effect and contribution to the transformation of the acute inflammation into chronic one.
描述了在免疫、气管内插入卡普纶线及其组合条件下家兔肺组织免疫形态学检查的结果。在所有情况下，肺的支气管血管和肺泡血管屏障均受到干扰，导致替代性、渗出性和增殖性病变的发展。炎症性病变在体液免疫和细胞免疫过程（包括免疫病理反应：组织的免疫复合物损伤以及可能的迟发型超敏反应）的参与下发展。所研究的肺炎变体的特征与抗原进入肺部的不同方式有关，显然也与肺部的定量和定性特征有关。免疫在炎症性肺病发病机制中的作用在于抗炎作用以及对急性炎症向慢性炎症转变的促进作用。
