种子提取物在体外抑制蛋白质合成。
Seed extracts inhibiting protein synthesis in vitro.
作者信息
Gasperi-Campani A, Barbieri L, Morelli P, Stirpe F
出版信息
Biochem J. 1980 Feb 15;186(2):439-41. doi: 10.1042/bj1860439.
Abstract
Of 33 seed extracts examined, 12 inhibited protein synthesis in a rabbit reticulocyte lysate. This activity seems to be due to a protein, since (i) it was recovered with the (NH4)2SO4 precipitate, (ii) it was retained by dialysis membranes, and (iii) in all cases but one was destroyed by boiling. Only the extracts from the seeds of Adenia digitata and, to a lower extent, of Euonymus europaeus inhibited protein synthesis in intact cells.
摘要
在所检测的33种种子提取物中，有12种抑制兔网织红细胞裂解液中的蛋白质合成。这种活性似乎归因于一种蛋白质，因为：（i）它可在硫酸铵沉淀中回收；（ii）它可被透析膜截留；（iii）除一种情况外，在所有情况下煮沸都会使其失活。只有来自指叶腺萼木种子的提取物，以及程度稍低的来自欧洲卫矛种子的提取物，会抑制完整细胞中的蛋白质合成。
相似文献
1
Seed extracts inhibiting protein synthesis in vitro.种子提取物在体外抑制蛋白质合成。
Biochem J. 1980 Feb 15;186(2):439-41. doi: 10.1042/bj1860439.
2
Inhibition of protein synthesis in vitro by proteins from the seeds of Momordica charantia (bitter pear melon).苦瓜种子蛋白对体外蛋白质合成的抑制作用。
Biochem J. 1980 Feb 15;186(2):443-52. doi: 10.1042/bj1860443.
3
Studies on the proteins from the seeds of Croton tiglium and of Jatropha curcas. Toxic properties and inhibition of protein synthesis in vitro.巴豆和麻疯树种子蛋白质的研究。毒性特性及体外对蛋白质合成的抑制作用。
Biochem J. 1976 Apr 15;156(1):1-6. doi: 10.1042/bj1560001.
4
Inhibition of in vitro protein synthesis in a rabbit reticulocyte cell-free system by toxic trypsic peptides from ricin.
Biochimie. 1974;56(9):1287-9. doi: 10.1016/s0300-9084(74)80023-4.
5
On the distribution of ribosome-inactivating proteins amongst plants.关于核糖体失活蛋白在植物中的分布
J Nat Prod. 1985 May-Jun;48(3):446-54. doi: 10.1021/np50039a013.
6
The nature of the differential inhibition of polyphenylalanine synthesis in extracts from Artemia salina and rabbit reticulocytes by the Phytolacca americana protein.美洲商陆蛋白对卤虫和兔网织红细胞提取物中聚苯丙氨酸合成的差异抑制性质。
Mol Biol Rep. 1976 Apr;2(5):363-7. doi: 10.1007/BF00366257.
7
Purification and properties of different forms of modeccin, the toxin of Adenia digitata. Separation of subunits with inhibitory and lectin activity.手指腺毛果毒素不同形式的纯化及性质。具有抑制活性和凝集素活性的亚基的分离。
Biochem J. 1980 Jan 1;185(1):203-10. doi: 10.1042/bj1850203.
8
The ribosome-inactivating, antiproliferative and teratogenic activities and immunoreactivities of a protein from seeds of Luffa aegyptiaca (Cucurbitaceae).
Gen Pharmacol. 1993 May;24(3):655-8. doi: 10.1016/0306-3623(93)90226-n.
9
Isolation and partial characterization of three protein-synthesis inhibitory proteins from the seeds of Luffa cylindrica.从丝瓜种子中分离出三种蛋白质合成抑制蛋白并进行部分特性鉴定。
Agric Biol Chem. 1990 Aug;54(8):2085-92.
引用本文的文献
1
Hyperuricaemia, Xanthine Oxidoreductase and Ribosome-Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research.高尿酸血症、黄嘌呤氧化还原酶与植物源核糖体失活蛋白：菲奥伦佐·斯特尔佩对前沿研究的贡献
Molecules. 2017 Jan 27;22(2):206. doi: 10.3390/molecules22020206.
2
Isolation and partial characterization of a new ribosome-inactivating protein from Petrocoptis glaucifolia (Lag.) Boiss.从蓝花绿绒蒿（Petrocoptis glaucifolia（Lag.）Boiss.）中分离和部分鉴定一种新核糖体失活蛋白。
Planta. 1992 Mar;186(4):532-40. doi: 10.1007/BF00198033.
3
Inhibition of protein synthesis in vitro by proteins from the seeds of Momordica charantia (bitter pear melon).苦瓜种子蛋白对体外蛋白质合成的抑制作用。
Biochem J. 1980 Feb 15;186(2):443-52. doi: 10.1042/bj1860443.
4
On the action of ribosome-inactivating proteins: are plant ribosomes species-specific?关于核糖体失活蛋白的作用：植物核糖体具有物种特异性吗？
Biochem J. 1982 Jan 15;202(1):279-80. doi: 10.1042/bj2020279.
5
Ribosome-inactivating proteins from the seeds of Saponaria officinalis L. (soapwort), of Agrostemma githago L. (corn cockle) and of Asparagus officinalis L. (asparagus), and from the latex of Hura crepitans L. (sandbox tree).肥皂草（石碱花）、麦仙翁和芦笋种子以及沙盒树乳汁中的核糖体失活蛋白。
Biochem J. 1983 Dec 15;216(3):617-25. doi: 10.1042/bj2160617.
6
Effect of ribosome-inactivating proteins on virus-infected cells. Inhibition of virus multiplication and of protein synthesis.核糖体失活蛋白对病毒感染细胞的作用。抑制病毒增殖和蛋白质合成。
Arch Virol. 1982;71(4):323-32. doi: 10.1007/BF01315062.
7
Bryodin, a ribosome-inactivating protein from the roots of Bryonia dioica L. (white bryony).白泻根素，一种从白泻根（Bryonia dioica L.）根部提取的核糖体失活蛋白。
Biochem J. 1986 Dec 15;240(3):659-65. doi: 10.1042/bj2400659.
8
Ribosome-inactivating proteins from plant cells in culture.来自培养植物细胞的核糖体失活蛋白。
Biochem J. 1989 Feb 1;257(3):801-7. doi: 10.1042/bj2570801.
9
Molecular recognition in antibodies and its application.抗体中的分子识别及其应用。
Experientia. 1991 Dec 1;47(11-12):1129-38. doi: 10.1007/BF01918377.
本文引用的文献
1
Synthesis of hemoglobin in a cell-free system. I. Properties of the complete system.无细胞体系中血红蛋白的合成。I. 完整体系的性质。
J Biol Chem. 1962 Mar;237:760-7.
2
Clonal growth in vitro of human cells with fibroblastic morphology; comparison of growth and genetic characteristics of single epithelioid and fibroblast-like cells from a variety of human organs.具有成纤维细胞形态的人细胞在体外的克隆生长；来自多种人体器官的单个上皮样细胞和成纤维细胞样细胞的生长及遗传特征比较。
J Exp Med. 1957 Jul 1;106(1):145-58. doi: 10.1084/jem.106.1.145.
3
Inhibition of protein synthesis in vitro by proteins from the seeds of Momordica charantia (bitter pear melon).苦瓜种子蛋白对体外蛋白质合成的抑制作用。
Biochem J. 1980 Feb 15;186(2):443-52. doi: 10.1042/bj1860443.
4
The phytohemagglutinin from sunn hemp seeds (Crotalaria juncea). Purification by biospecific affinity chromatography.来自菽麻种子（猪屎豆）的植物血凝素。通过生物特异性亲和色谱法进行纯化。
Biochim Biophys Acta. 1973 Jun 15;310(2):446-52. doi: 10.1016/0005-2795(73)90128-1.
5
The effect of an antiviral peptide on the ribosomal reactions of the peptide elongation enzymes, EF-I and EF-II.一种抗病毒肽对肽链延伸酶EF-I和EF-II核糖体反应的影响。
Arch Biochem Biophys. 1973 Apr;155(2):278-89. doi: 10.1016/0003-9861(73)90116-1.
6
Purification and partial characterization of the antiviral protein from Phytolacca americana which inhibits eukaryotic protein synthesis.美洲商陆中抑制真核生物蛋白质合成的抗病毒蛋白的纯化及部分特性分析
Arch Biochem Biophys. 1975 Aug;169(2):522-8. doi: 10.1016/0003-9861(75)90195-2.
7
Inhibition of protein synthesis in vitro by crotins and ricin. Effect on the steps of peptide chain elongation.巴豆毒素和蓖麻毒素对体外蛋白质合成的抑制作用。对肽链延伸步骤的影响。
Biochem J. 1976 Apr 15;156(1):7-13. doi: 10.1042/bj1560007.
8
Studies on the proteins from the seeds of Croton tiglium and of Jatropha curcas. Toxic properties and inhibition of protein synthesis in vitro.巴豆和麻疯树种子蛋白质的研究。毒性特性及体外对蛋白质合成的抑制作用。
Biochem J. 1976 Apr 15;156(1):1-6. doi: 10.1042/bj1560001.
9
An ATP-dependent inhibition of protein synthesis in ascites cell extracts by wheat germ protein.小麦胚芽蛋白对腹水细胞提取物中蛋白质合成的ATP依赖性抑制作用。
Biochim Biophys Acta. 1977 Nov 2;479(1):31-8. doi: 10.1016/0005-2787(77)90123-x.
10
Inhibition of protein synthesis by seed-extracts. A screening study.
FEBS Lett. 1977 Apr 15;76(2):173-6. doi: 10.1016/0014-5793(77)80145-2.
Zotero 插件