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斑驳小鼠突变体中的铜代谢。64Cu向胎儿花斑(Mobr)小鼠的胎盘转运缺陷。

Copper metabolism in mottled mouse mutants. Defective placental transfer of 64Cu to foetal brindled (Mobr) mice.

作者信息

Mann J R, Camakaris J, Danks D M

出版信息

Biochem J. 1980 Feb 15;186(2):629-31. doi: 10.1042/bj1860629.

Abstract

Decreased placental transfer of 64Cu into both Mobr/Y and Mobr/+ foetuses was apparent after its administration to pregnant Mobr/+ mice. The severity of impairment and the degree of retention and accumulation of 64Cu in the placenta was not as great as has been previously observed in the gut of the suckling Mobr/Y mice.

摘要

给怀孕的Mobr/+小鼠注射64Cu后,明显发现其向Mobr/Y和Mobr/+胎儿的胎盘转运减少。64Cu在胎盘中的损伤严重程度以及保留和积累程度不如先前在哺乳期Mobr/Y小鼠的肠道中观察到的那样严重。

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