Kramis R, Vanderwolf C H
Brain Res. 1980 Jun 23;192(2):383-98. doi: 10.1016/0006-8993(80)90891-4.
Hippocampal electrographic patterns comprised of specific frequencies of slow waves electrographically similar to the waves comprising normal hippocampal rhythmical slow activity (RSA, theta) may be generated by appropriate electrical stimulation of specific septal, hypothalamic, and brain stem sites. The waves elicited from some but not all sites are further similar to normal RSA patterns in that they may be differentiated into atropine-sensitive (immobility-related) and atropine-resistant (movement-related) types by the same criteria used to define atropine-sensitive and atropine-resistant RSA. The high degree of behavioral, pharmacological, and electrographic similarity between the electrically elicited hippocampal activity and normal hippocampal RSA would seem to warrant further use of the present technique in the investigation of hippocampal function.
海马电图模式由特定频率的慢波组成，这些慢波在电图上与构成正常海马节律性慢活动（RSA，θ波）的波相似，可通过对特定的隔区、下丘脑和脑干部位进行适当的电刺激产生。从某些但并非所有部位引出的波在进一步的方面与正常RSA模式相似，即通过用于定义对阿托品敏感和耐药的RSA的相同标准，它们可被区分为对阿托品敏感（与不动相关）和对阿托品耐药（与运动相关）的类型。电诱发的海马活动与正常海马RSA之间在行为、药理学和电图方面的高度相似性，似乎保证了在海马功能研究中进一步使用本技术。
