Kasting N W, Veale W L, Cooper K E
Can J Physiol Pharmacol. 1980 Mar;58(3):316-9. doi: 10.1139/y80-054.
Arginine vasopressin (AVP) was administered into the lateral cerebral ventricles of rats to assess its effects when given directly into the brain. AVP (1.0 microgram) caused an immediate sharp decrease in body temperature. Behaviorally, AVP caused short pauses of immobility and staring upon the first injection but the same dose caused myoclonic-myotonic convulsions upon the second injection 2 days later. Thereafter, as little as 10 ng of AVP caused seizures.
将精氨酸加压素（AVP）注入大鼠侧脑室，以评估直接注入脑内时的作用。AVP（1.0微克）可使体温立即急剧下降。行为上，首次注射AVP会导致短暂的静止不动和凝视停顿，但2天后第二次注射相同剂量时会引发肌阵挛 - 强直性惊厥。此后，低至10纳克的AVP即可引发癫痫发作。
