Orsini J A, Taylor J I
Cornell Vet. 1980 Jan;70(1):50-66.
Enflurane, a new volatile anesthetic agent, was compared with halothane as components of a commonly used clinical anesthetic regime in the pony. Enflurane provides satisfactory general anesthesia when administered at a maintenance concentration of approximately 1.5-2.5%, in combination with a 1:1 nitrous oxide-oxygen mixture. With both agents cardiac rhythm and pulse were stable, however significant arterial hypotension occurred, especially during and following induction, being anesthetic concentration dependent. Hypoventilation was induced by both agents, there being no significant quantitative difference in respiratory depression despite significantly lower respiratory rates with enflurane. Serum electrolytes and liver enzymes did not change significantly with either regime. Emergence from anesthesia was smooth, and significantly more rapid with enflurance. Post-anesthetic complications were not observed with either agent.
安氟醚是一种新型挥发性麻醉剂,在小马常用的临床麻醉方案中,将其与氟烷进行了比较。当以约1.5 - 2.5%的维持浓度与1:1的氧化亚氮 - 氧气混合物联合使用时,安氟醚可提供令人满意的全身麻醉。两种药物使用时,心律和脉搏均稳定,但均出现明显的动脉低血压,尤其是在诱导期间和诱导后,且与麻醉浓度有关。两种药物均引起通气不足,尽管使用安氟醚时呼吸频率明显较低,但在呼吸抑制方面没有显著的定量差异。两种方案下血清电解质和肝酶均无明显变化。麻醉苏醒平稳,使用安氟醚时苏醒明显更快。两种药物均未观察到麻醉后并发症。