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组胺对血管平滑肌收缩的相性和紧张性成分的作用。

Action of histamine on phasic and tonic components of vascular smooth muscle contraction.

作者信息

Watkins R W, Davidson I W

出版信息

Experientia. 1980 May 15;36(5):582-4. doi: 10.1007/BF01965815.

DOI:10.1007/BF01965815
PMID:7379965
Abstract

The isometric contractile response of rabbit aortic strips in response to histamine was studied. Biphasic dose-dependent contractions reflecting release of internal Ca2+ (phasic component) and simultaneous mobilization of external Ca2+ stores (tonic component) were produced.

摘要

研究了兔主动脉条对组胺的等长收缩反应。产生了反映内部Ca2+释放(相性成分)和外部Ca2+储存同时动员(紧张性成分)的双相剂量依赖性收缩。

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本文引用的文献

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Vascular Smooth Muscle: Dual Effect of Calcium.血管平滑肌:钙的双重作用。
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Differential effects of calcium removal upon vascular smooth muscle contraction induced by norepinephrine, histamine and potassium.去除钙对去甲肾上腺素、组胺和钾诱导的血管平滑肌收缩的不同影响。
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Arch Int Pharmacodyn Ther. 1972 Apr;196:Suppl 196: 35-.
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Relative contributions of Ca2+ influx and cellular Ca2+ release during drug induced activation of the rabbit aorta.药物诱导兔主动脉激活过程中Ca2+内流和细胞内Ca2+释放的相对贡献。
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Blockade of membrane calcium fluxes by lanthanum in relation to vascular smooth muscle contractility.镧对膜钙通量的阻断与血管平滑肌收缩性的关系
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