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肝硬化肝脏中的阿米巴脓肿。

Amoebic abscess in the cirrhotic liver.

作者信息

Falaiye J M, Okeke G C, Fregene A O

出版信息

Gut. 1980 Feb;21(2):161-3. doi: 10.1136/gut.21.2.161.

Abstract

Though amoebic liver abscess and liver cirrhosis occur very commonly in hospital practice in the tropics, they have not to the knowledge of the present authors hitherto been reported to occur simultaneously in the same patient. The patient described here, who had clear-cut clinical and histological features of chronic liver cirrhosis with portal hypertension and ascites, presented somewhat acutely with liver pain and an amoebic liver abscess that contained 'chocolate sauce' on needle aspiration. The amoebic abscess, although, no doubt, superimposed on chronic irreversible cirrhosis, rapidly regressed on metronidazole therapy. The infrequency with which liver abscess and liver cirrhosis coexist cannot be satisfactorily explained. It is probable, however, that extensive scarring in the liver may prevent entamoeba histolytica from thriving.

摘要

虽然阿米巴肝脓肿和肝硬化在热带地区的医院临床实践中非常常见,但据本文作者所知,此前尚未有报道称这两种疾病会在同一患者身上同时出现。这里描述的患者具有明确的慢性肝硬化临床和组织学特征,伴有门静脉高压和腹水,却突然出现肝区疼痛,并经穿刺抽出含有“巧克力酱”样物质的阿米巴肝脓肿。尽管这个阿米巴脓肿无疑是叠加在慢性不可逆性肝硬化之上,但在甲硝唑治疗后迅速消退。肝脓肿和肝硬化同时存在的情况很少见,目前尚无法得到令人满意的解释。然而,肝脏广泛的瘢痕形成可能会阻止溶组织内阿米巴的生长繁殖。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30a0/1419366/f29441b2d0bb/gut00435-0094-a.jpg

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