乙炔基底物对肝细胞色素P-450的自催化失活作用。 - Suppr

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超能文献

Self-catalyzed inactivation of hepatic cytochrome P-450 by ethynyl substrates.

作者信息

Ortiz de Montellano P R, Kunze K L

出版信息

J Biol Chem. 1980 Jun 25;255(12):5578-85.

PMID:7380828

Abstract

摘要

相似文献

Self-catalyzed inactivation of hepatic cytochrome P-450 by ethynyl substrates.乙炔基底物对肝细胞色素P-450的自催化失活作用。

J Biol Chem. 1980 Jun 25;255(12):5578-85.

Metabolic activation of acetylenic substituents to derivatives in the rat causing the loss of hepatic cytochrome P-450 and haem.大鼠体内乙炔取代基代谢活化为衍生物，导致肝细胞色素P-450和血红素丧失。

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Structure-activity relationships in the destruction of cytochrome P-450 mediated by certain ethynyl-substituted compounds in rats.大鼠体内某些乙炔基取代化合物介导的细胞色素P-450破坏中的构效关系

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