通过外源性途径激活因子IX的动力学。米氏常数（Km）对组织因子的依赖性。 - Suppr

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超能文献

Kinetics of factor IX activation via the extrinsic pathway. Dependence of Km on tissue factor.

作者信息

Zur M, Nemerson Y

出版信息

J Biol Chem. 1980 Jun 25;255(12):5703-7.

PMID:7380833

Abstract

摘要

相似文献

Kinetics of factor IX activation via the extrinsic pathway. Dependence of Km on tissue factor.通过外源性途径激活因子IX的动力学。米氏常数（Km）对组织因子的依赖性。

J Biol Chem. 1980 Jun 25;255(12):5703-7.

Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation.组织因子与因子VII的反应产物对因子IX的激活：启动血液凝固的额外途径。

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Redetermination of the rate-limiting step in the activation of factor IX by factor XIa and by factor VIIa/tissue factor. Explanation for different electrophoretic radioactivity profiles obtained on activation of 3H- and 125I-labeled factor IX.对因子XIa以及因子VIIa/组织因子激活因子IX过程中限速步骤的重新测定。对3H和125I标记的因子IX激活时获得的不同电泳放射性图谱的解释。

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Blood coagulation.血液凝固

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Tissue factor accelerates the activation of coagulation factor VII: the role of a bifunctional coagulation cofactor.

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Hemophilia B with mutations at glycine-48 of factor IX exhibited delayed activation by the factor VIIa-tissue factor complex.在凝血因子IX第48位甘氨酸处发生突变的B型血友病患者，其凝血因子VIIa-组织因子复合物的激活出现延迟。

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Tissue factor and hemostasis.组织因子与止血

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A sequential mechanism for exosite-mediated factor IX activation by factor XIa.因子 XIa 通过因子 IX 上的变构结合位点进行激活的级联机制。

J Biol Chem. 2012 Nov 2;287(45):38200-9. doi: 10.1074/jbc.M112.376343. Epub 2012 Sep 7.

Surface-mediated control of blood coagulation: the role of binding site densities and platelet deposition.表面介导的血液凝固控制：结合位点密度和血小板沉积的作用。

Biophys J. 2001 Mar;80(3):1050-74. doi: 10.1016/S0006-3495(01)76085-7.

Complementary DNA sequencing of canine tissue factor pathway inhibitor reveals a unique nanomeric repetitive sequence between the second and third Kunitz domains.

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Novel antithrombotic drugs in development.正在研发的新型抗血栓药物。

Drugs. 1995 Jun;49(6):856-84. doi: 10.2165/00003495-199549060-00002.

Acquired antibody to factor XI in a patient with congenital factor XI deficiency.一名先天性因子 XI 缺乏症患者体内获得性因子 XI 抗体。

J Clin Invest. 1982 Jun;69(6):1270-6. doi: 10.1172/jci110566.

Characterization of the defect in activation of factor IX Chapel Hill by human factor XIa.人因子XIa对因子IX Chapel Hill激活缺陷的特征分析。

J Clin Invest. 1981 Dec;68(6):1420-6. doi: 10.1172/jci110393.

Kinetics of the Factor XIa catalyzed activation of human blood coagulation Factor IX.凝血因子XIa催化人凝血因子IX活化的动力学

J Clin Invest. 1984 May;73(5):1392-9. doi: 10.1172/JCI111343.

Cleavage and inactivation of Factor IX by granulocyte elastase.粒细胞弹性蛋白酶对凝血因子IX的裂解与失活作用。

J Clin Invest. 1983 Nov;72(5):1706-15. doi: 10.1172/JCI111130.

Binding of factors IX and IXa to cultured vascular endothelial cells.凝血因子IX和IXa与培养的血管内皮细胞的结合。

Proc Natl Acad Sci U S A. 1983 Jul;80(13):4119-23. doi: 10.1073/pnas.80.13.4119.

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